If one had the budget, and know-how, I believe the novel "Pudd'n head Wilson" could be the next huge block buster. Ideally, this novel could cause heaps of controversy. In regard to the one drop rule as applied to characters in this novel, choosing actresses and actors would be arduous yet interesting. The viewers could really become surprised at discovering certain characters are not exactly as they seem.
First, I would try to get President Obama in the cast, simply for a little extra press. Next, I would aim to cast Beyonce, Halle Berry, or possibly Gabrielle Union as the star female actress. As for Pudd'n Head Wilson, I think Morgan Freeman or Denzel Washington would be perfect, due to their successful careers and popularity as actors. Finally, casting the two twins would call for some investigating, I would need the perfect complexion as well as a large degree of identical features between the two. Real life twins would be perfect.